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  • 147Consider using Zstandard and/or LZ4 instead of Deflate (github.com)
    by marklit10 hours ago | 12 comments
  • 181Ozempic shows anti-aging effects in trial (trial.medpath.com)
    by amichail13 hours ago | 21 comments
  • 317Scientific fraud has become an 'industry,' analysis finds (science.org)
    by pseudolus17 hours ago | 44 comments
  • 751Things that helped me get out of the AI 10x engineer imposter syndrome (colton.dev)
    by coltonv14 hours ago | 112 comments
  • 694Claude Opus 4.1 (anthropic.com)
    by meetpateltech11 hours ago | 29 comments
  • 155Ask HN: Have you ever regretted open-sourcing something?
    by paulwilsonn3 days ago | 42 comments
  • 42Cow vs. Water Buffalo Mozzarella (2011) (itscheese.com)
    by indigodaddy3 days ago | 13 comments
  • 1Kyber (YC W23) is hiring enterprise account executives (ycombinator.com)
    7 hours ago |
  • 39Show HN: Stagewise (YC S25) – Front end coding agent for existing codebases (github.com)
    by juliangoetze13 hours ago | 14 comments
  • 997uBlock Origin Lite now available for Safari (apps.apple.com)
    by Jiahang19 hours ago | 62 comments
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